This is all the hand holding you are getting. I just did a quick search and found several good articles.
http://scholar.google.com/
Working in EMS and on Specialty transports for several years, I also have experience that tells me what patients go through. It's not rocket science, just a little commonsense.
Thanks for removing the personal shot (serious).
I didn't need any hand holding. I'm familliar with google scholar...just as a for instance...type in "'lights and sirens' stroke" The first page of results has one vague reference to transport with L/S...every other article on the first 2 pages of results deals with dispatch priority not transport with or without lights and sirens. The closest to a mention of ambulance transport time is just listing net time with patient, the effects of prehospital recognition on stroke, and the fact that pt.s presenting with stroke-like symptoms to an ED get CT's faster than pts comming by POV.
The point is, there is no good research that I've yet seen which directly addresses the use of lights and sirens transport with stroke patients.
There is (decent to good) evidence that early treatment = better outcome in strokes. Insofar as in many locations L/S will reduce transport time by signifigant amounts, it is logical to assume that absent any other intervening factor (eg stress...see below), L/S will improve outcomes.
Stroke team activation is obviously important. no they don't materialize, but in a properly setup system, they are ready when the ambulance shows up. Door to CT times are important...but if you don't hit the door for 40 minutes instead of 15, than patient outcome may well be worse.
So from the premise that L/S decreases onset-treatment times, which is good. L/S is a good practice, unless there is a signifigant evidence supported detriment to such transport. Accident rates are certianly valid, but proper driver training and re-enforcement can reduce those risks. In my case I' don't drive like a nut, so i don't think the increased accident rate is an accurate representation of the risk to me and my patient individually.
I understand the stress response arguments - they would be an intervening factor that might outweigh the time saved by L/S driving. I don't agree that they do based on everything I know about the effects of stress on strokes. I will readily grant (and already have) that stroke outcome is worsened by stress responses - especially the inflammatory, hyperglycemic, and hyperthermic variety.
The argument that L/S increases stress is not enough. This issue is more complicated than that, and the quantity of stress matters. I've seen the data for time to treatment, I want to see the data (actual numbers, not generalizations) for stress responses. I don't believe such data exists specifically applied to L/S transport. There is a lot of animal data about stress and stroke outcome, but it is mostly chronic or subacute stress prior to stroke. I knew about this data already, and spent the last hour or so looking again to confirm that...I didn't find anything too specific to the issue at hand.
There is data which indicates that there is a stress response to stroke regardless of psychological stress (which is what L/S is). Thus we are not comparing stress from L/S to an unstressed CNS, rather the incremental additive stress form L/S transport to the stress that already exists from the physiological response to stroke, underlying pathologies and disease processes, possibly a freaked out family, psychogical disturbance due to strange neurologic symtoms (e.g. not being able to talk is pretty darn stressful), stress from the arrival of an ambulance, quick moving providers, phone conversatoins with all kinds of medical gibberish, going in an ambulance, exposure to a hospital, etc.
I find it hard to believe that hearing a siren in the back (when the patient likely expects a siren to go with an ambulance anywyas) is going to make that much quantitiave difference in net stress levels. In the absence of data (and for this, I will ask for citations. I've looked, and found nothing on point about stress increases in patients (plenty about providers) when brought by ambulance), we are left to guess...and that's my guess.
So, from my perspective...for all you evidence based types out there
decent-good evidence supports decreasing onset to treatment times
good evidence says stress is bad in a stroke, but thats prior chronic stress, acute stress almost certianly is bad, but exists anyways
little-no evidence that L/S has any effect at all on overall stress levels
To me that adds up to the evidence pointing to L/S (in systems where it make a signifigatn difference in transport time) as possibly helping outcomes until more evidence clearly demonstrates a detriment.
Fire away...i may not answer anymore tonight. Tomorrow is another day...
Note: I realize I'm not paying any attention to MI's AAA's or the other things I mentioned. I'll admit I'm not nearly so familiar with that data, and I don't have time to debate each condition individually, so i picked strokes as my example condition. I got blasted for advocating strokes to L/S too, so I figured it's as good a condition to defend as any...