Caution: Paralyzing Agent
A single dose of etomidate does not effect peri-induction/intubation adrenal function. The association with adrenal insufficiency affecting outcome is controversial in specific patient groups. I give etomidate to intubate unstable patients all day, every day.Etomidate has a known adrenal suppressive effect and at this point probably the only reason you have a pressure of 100 systolic is a last-ditch catecholamine dump. Blunt that with etomidate and that turns into a bad day quickly.