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The above is GREAT if you're giving weight-based medications. Very handy and basically what I do if I must make those calculations myself.There are only 2 simple steps to calculate a drug given by IVP:
- First, figure out how much drug you need to administer. This is simply the known dose x the patients weight in kg. For example, the ped dose of Ancef is 25 mg/kg. So if you have a 10 kg kid, you just multiply 25x10. 250 mg is your total dose to give.
Another one: you need to give 1 mcg/kg of fentanyl to a 75kg patient. First, calculate the total dose: 1mcg x 75kg = 75 mcg. Now, you need to covert 75mcg to a volume to give. Your fentanyl is 50mcg/ml. So now divide your dose by your concentration: 75 / 50 = 1.5 ml to give.
- Second, convert the amount of drug you are need to give (in mcg or mg) to a volume (number of cc's) to give. This is simply the dose of the drug you are going to give divided by the concentration you have on hand. So if your Ancef comes in a concentration of 100mg/ml. you divide your dose (250) by your concentration (100). 250/100 = 2.5. That the number of cc to give.
That's all there is to it: multiply the ordered dose by the patient's weight, and then divide that number by the concentration on hand. Done.
This is good for those times when you know you need to give a drug dose that's different from unit dose that you have on hand. A couple weeks ago I had to give an antibiotic that we didn't have the particular dose in stock anywhere in the hospital but we did have it available in another dose. I used this formula to determine how much of the antibiotic to give.Similar to (ordered/available)*(vehicle).
So if you need to give 2mg of Zofran (4mg/2ml):
(2mg/4mg)*(2ml)=1ml. Therefore, give 1ml.
I like this method because it works for any concentration, you don't have to get it down to blank/1ml. In addition, it's nice because you can use it for pills too:
You need to give 4mg of Zofran ODT. You have 8mg tabs. How many do you give?
(4mg/8mg)*(1 tab)=0.5 tabs.
Fortunately a lot of the time you only need to give full unit doses...