epi was removed from our cardiac arrest protocols in 2008.
What area of Canada?
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epi was removed from our cardiac arrest protocols in 2008.
I have little doubt that the AHA will not change it's stance in the next round of updates. I have little faith in an organisation that quotes it's own previous guidelines as evidence for it's current guidelines.
Hopefully what these studies will do is make it possible to run a real trial such as was attempted in Western Australia. It is a bit hard to maintain that epi is standard of care when there are so many observational studies that demonstrate harm.
I'm excited to hear that at least one service has removed epi, there is hope for us all yet! Medic Tim, has there been any examination of before and after data since eliminating it from the protocol?
Hopefully what these studies will do is make it possible to run a real trial such as was attempted in Western Australia. It is a bit hard to maintain that epi is standard of care when there are so many observational studies that demonstrate harm.
Lets be fair here - they did NOT demonstrate harm. They only demonstrated a correlation with harm, which as we all know does not equal causation. When considering the 2 RCTs (one of which was double blind), we should recall that they both trended in favor of epi and did not demonstrate harm.
The post hoc analysis of the IV vs. no IV study in Sweden demonstrated pretty well why all these retrospective, observation studies may be inherently biased against epi - all the patients with the best chances of survival (those that respond early to CPR and defibrillation) will be placed in non-epi group as they will gain ROSC before epi is administration. And it is also worth noting that the original study was designed based on retrospective, observational studies and their outcomes came no where close to matching the observed outcomes of previous studies, thus their study was grossly underpowered to detect a benefit. With the 2 RCTs available, I think future research will be (hopefully) more robust and better designed.
And while a before-and-after study of epi use in New Brunswick will probably be better able to inform of us of epi's impact on outcomes, it will still be less informative than a double blind, placebo controlled trial. Hopefully, IRBs in the US and around the world will grow "a pair" and allow research to be undertaken.
Anyhow, it will be interesting to see how AHA responds. I think the argument for epi will be based on the lack of harm demonstrated in the RCTs and they'll keep it based on that. I think what would be best is to give it an indeterminate status, since, well, it really is undetermined whether it is harmful or beneficial. Because AHA is viewed as the authority that sets the standard of care for ACLS, I think the only way any RCTs on epi will occur in the US is if they no longer recommend it. When everything comes up for review, it may be worth sending some letters in their direction.
Epi has not shown any benefit in 40 years. We do not give medication based simply on doing no harm.
There is also no way to tell wether or not renal and cerebral insult from an arrest is made worse by epi or not. However, there is a fair amount of basic science that catecholamines do have an impact on circulation of such.
If endogenous catecholamine has effect, certainly exogenous epi does.
I agree with smash, AHA will do nothing. Writing them ltters is a waste of time. There is always an excuse as to why epi is never removed.
epi was removed from our cardiac arrest protocols in 2008.
There is little I disagree with. I personally think clinicians should be more involved. Concluding that all attempts to influence the AHA or some organization is futile is declaring defeat before the battle, in my opinion.
I think that the best approach would be to start by getting another already established organization or group of them to endorse different guidlines.
I would even suspect that getting a handful of medical colleges to do so would be a fair challenge against AHA supremacy. (which clearly needs to be challenged)
What are your protocols for cardiac arrest if you don't mind me asking?
oddly enough, this was discussed between one of the field bosses (who is a medic) and myself (an uneducated EMT). He told me ACLS wasn't mandatory, it's just easier than having your medical director write his or her own protocols, as well as stands up better in a lawsuit since it is the standard of care.If it's reasonable to believe that the AHA won't change their stance maybe clinicians should not associate with them. Instead of saying "Use AHA recommendations", they could write their own recommendations. That would probably be easier.
Yond Veneficus has a lean and hungry look.
Methinks there is much reason in his sayings.
At the end of the day, it is inherently difficult to take all of the information available and reduce it to a simple flow-chart that you can teach to any doofus who has 16 hours to spare. ACLS isn't really about diving through all of the information, it is about teaching a provider how to run a code based on expert recommendations.
I think the negativity towards AHA stems from this. Someone said it in another post but AHA would have a tough time selling ACLS cards if all they had to teach was CPR and early defib. Business and politics, as usual, muddy up the science. As for diving through all the information and developing treatment recommendations...well, that is the point of their existence. They are the ones claiming authority. Also I might add that the videos and teaching methods are pretty lame. When you teach at the 'any doofus who has 16 hours to spare' level you shouldn't be surprised that intelligent people get turned off.
The paper they publish is usually pretty good, except when things appear and disappear without explanation and the paper cites previous iterations of itself as evidence. I'm happy with some of the things they do, such as the hands only cpr initiative and advocating for healthier lifestyles. But you have to wonder what exactly changes hands in order for a product to get that AHA seal of approval...
I think the negativity towards AHA stems from this. Someone said it in another post but AHA would have a tough time selling ACLS cards if all they had to teach was CPR and early defib. Business and politics, as usual, muddy up the science.
... But you have to wonder what exactly changes hands in order for a product to get that AHA seal of approval...
maybe we should take a breather and leave it alone.
The BLS/ACLS guidelines aren't meant to do that; they're baseline recommendations, and increasingly the AHA is emphasizing that they are broad recommendations rather than rules.