In Alberta we've been using it for almost 10 years. Started off as a trial in 2003-2006 and now part of STEMI protocol.
STEMI identified with protocol meeting elevation, associated S/S, 12 lead transmitted to one of a dozen Cardiologists on call provincially, follow up with a phone call and clinical discussion with the Dr, factors considered such as transport time, cath lab availability, severity of the STEMI, etc. Consent form and relative/absolute contraindications reviewed, drugs given (plavix, IV& SC Enoxaparin (age based), and tPa IV. Alternative PCI route if available - Brilinta, Enoxaparin, transport direct to PCI suite. Personally I have probably done about 15 enrolments to date with approximately 50% going tPa rotue.
This is not reserved for rural applications, in fact the start of this trial in 2003 was in an 1 million pop. urban area. 2 locations in Edmonton that provide primary PCI.
As for CVA i doubt that will ever be seen in EMS in this Province.. The Alberta Provincial Stroke Strategy has enabled the province to establish availability of a CT scan within the window of thrombolytic for CVA (4.5 hours is standard here with trials up to 6 hours). Rapid transport to a Stroke site or a alternative stroke site (with CT and teleconference with Neurologists) then administration of the thrombolytic as required.