The department deployed the AutoPulses with paramedic supervisors who used them when they encountered arrests in progress. Using age, gender and length of resuscitation efforts, results from the AutoPulse cases were then compared to results from comparable cases in which standard CPR was used, with a primary endpoint of patient arrival at the ED with spontaneous circulation.
The AutoPulse showed an improvement: 39% of patients on whom it was used had ROSC upon ED arrival, while 29% of regular-CPR patients did. This improvement was clearest among those with initial presenting rhythms of asystole (37% vs. 22%) or pulseless electrical activity (38% vs. 23%).
Some cautions, though: Because the SFFD’s investigation was not designed as an outcome study, its methodology was not optimal—case-matching is a fairly imprecise way to compare results. Also, because it had only four devices, the department gave them to the roving supervisors, who responded to every arrest, but not with the first-arriving crews. “And that,” says Isaacs, is where youd expect that a device that provides tremendous CPR and doesnt fatigue, like a rescuer would, to have its greatest benefit—in the first few minutes of an arrest.
At roughly the same time, a study in Richmond, VA, was showing similar promise.2 This study compared ROSC percentages in adult non-traumatic cardiac arrests from five years before and six months following a switch to the AutoPulse. Investigators found that using the AutoPulse yielded a 74% relative increase in ROSC over standard CPR. This increase occurred regardless of the patients initial cardiac rhythm. Overall, ROSC for all patients increased from 21.6% to 37.5%.