Great topic! It's a good area to review, and paramedics should know this stuff cold.
That said, there's a lot of misinformation, myth, or outdated stuff out there. I've reviewed this topic a few times in "
Anaphylaxis Knowledge Among Paramedics", "
New Guidelines for Anaphylaxis ", and "
Anaphylactic reactions - 5 things. ".
Let me just put out a few "controversial" statements that are actually part of the conventional thinking, based in the research, and are in the guidelines (read my reviews for links to sources).
Epi is the only medicine for anaphylaxis.
There is no evidence that steroids or antihistamines do anything for anaphylaxis, or even that do they do anything to prevent "biphasic" anaphylaxis. One study protocol used
only epi for anaphylaxis (and O2 and NS), and patients did fine.
Anaphylaxis is more than hypotension and stridor.
In fact, GI symptoms are a very concerning element of anaphylaxis, and are part of the standard definition of anaphylaxis.
Urticaria and vomiting, after exposure to a likely allergen, is anaphylaxis, according to the experts.
Anaphylaxis causes MIs
While there are case reports of people having problems with epi, usually after receiving whopping IV doses (e.g 100 µg), there are also plenty of reports of people having MIs due to untreated anaphylaxis - it's called
Kounis syndrome.
There are no absolute contraindications to epi
Is someone just has some itchy skin, that's not anaphylaxis. But true anaphylaxis needs true treatment, and the expert
EPs and allergists agree (pdf download) - there is no absolute contraindication to epi.
If you think I'm being controversial, just check out the sources, and see what you think!