Aussieaid
Forum Ride Along
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Hmmm, interesting thread. I agree that sometimes you can have too much of a good thing but in other circumstances a patient may look like they are fine but really at a cellular level they aren't. I think it requires a solid knowledge base and thinking skills to know when and how much oxygen to use. Unfortunately it seems like most protocols subscribe to the all or nothing theories to account for the lowest common denominators.
There is growing evidence that O2 can be harmful in simple MIs as well as newborns (especially premature) and some cardiac defects. In MIs hyperoxia is known to increase coronary artery tone which can lead to decreased coronary artery blood flow. It also causes a decreased cardiac output and stroke volume. Not to mention the damage from free radical production. Of course if the pt has cardiogenic shock, CHF or other complicating factors they are going to need that extra oxygen.
On the other hand there are 4 types of hypoxia not just hypoxic hypoxia: Hypoxic hypoxia where there is decreased oxygen in the air or an inability for it to diffuse across the lungs (most common type). Eg: lung disease, altitude.
Hypemic hypoxia where there is a reduction in the oxygen carrying capacity of the blood. Eg: anemia, bleeding, CO poisoning
Stagnant hypoxia (or distributive) where there is reduced cardiac output. Eg. CHF, hypovolemia, arterial stenosis.
Histotoxic hypoxia is where the O2 is available but the cells can't "take" or use the O2 from the blood. Eg: cyanide poisoning.
What this is leading to is that even though a pt's pulse oximeter reading is giving you a "good" number that may not equate to adequate oxygenation of the patient. Someone with CO poisoning may have a great SpO2 number and still be extremely hypoxic as the oximeter is actually reading the carboxyhemoglobin as oxyhemoglobin. You also have to lose a significant amount of blood sometimes before it is reflected in your pulse oximeter reading. One of the first signs of hypoxia is often agitation before you start seeing significantly decreased numbers. In some pts they need the extra oxygen for increased metabolic oxygen demands such as in sepsis or fevers.
So, yes you can do harm with oxygen but you can also do significant harm by withholding it when it is warranted even without significant signs of hypoxia. In other words you need to use sound clinical judgment before just withholding it on the majority of pts or giving it to everyone.
Sorry I got a little carried away and rambled a bit. :blush:
There is growing evidence that O2 can be harmful in simple MIs as well as newborns (especially premature) and some cardiac defects. In MIs hyperoxia is known to increase coronary artery tone which can lead to decreased coronary artery blood flow. It also causes a decreased cardiac output and stroke volume. Not to mention the damage from free radical production. Of course if the pt has cardiogenic shock, CHF or other complicating factors they are going to need that extra oxygen.
On the other hand there are 4 types of hypoxia not just hypoxic hypoxia: Hypoxic hypoxia where there is decreased oxygen in the air or an inability for it to diffuse across the lungs (most common type). Eg: lung disease, altitude.
Hypemic hypoxia where there is a reduction in the oxygen carrying capacity of the blood. Eg: anemia, bleeding, CO poisoning
Stagnant hypoxia (or distributive) where there is reduced cardiac output. Eg. CHF, hypovolemia, arterial stenosis.
Histotoxic hypoxia is where the O2 is available but the cells can't "take" or use the O2 from the blood. Eg: cyanide poisoning.
What this is leading to is that even though a pt's pulse oximeter reading is giving you a "good" number that may not equate to adequate oxygenation of the patient. Someone with CO poisoning may have a great SpO2 number and still be extremely hypoxic as the oximeter is actually reading the carboxyhemoglobin as oxyhemoglobin. You also have to lose a significant amount of blood sometimes before it is reflected in your pulse oximeter reading. One of the first signs of hypoxia is often agitation before you start seeing significantly decreased numbers. In some pts they need the extra oxygen for increased metabolic oxygen demands such as in sepsis or fevers.
So, yes you can do harm with oxygen but you can also do significant harm by withholding it when it is warranted even without significant signs of hypoxia. In other words you need to use sound clinical judgment before just withholding it on the majority of pts or giving it to everyone.
Sorry I got a little carried away and rambled a bit. :blush: