Low BG unresponsive to Glucagon / D50

MJordan2121

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Typical call with atypical results:

So, I was dispatched to a local nursing home for an 82 y/o female pt who was hypoglycemic, I thought, ok, check glucose, rule out other possibilities, give her some D50 and perk her up - pretty typical call. We get vitals, do a 12-lead, all normal, BG not so good - 44 and dropping. Initial BG by nursing facility was 55, so they nurses there are having a panic attack upon our arrival. She was a bit clammy, would answer our questions to the best of her ability, which wasn't too bad for a hypoglycemic demented patient. She could at least tell us who she was and what city she was in. While my partner was hooking her up to the monitor and getting vitals, I was actively searching for a vein, which was a nightmare. Since nothing was visible or palpable and this lady, I visualized the veins anatomically and attempted a blind stick to the AC - nope! This lady had a good 12 bruises to her left arm alone from previous attempts from a recent hospital visit and her right arm is not accessible due to over 100 stitches and multiple fractures and a recent surgery to fix it up. I look for veins in other areas without success.

Since we were 1 mile from ER, I just gave Glucagon and tx rapidly. Rechecked sugar, another finger stick, now down to 20. Pt is still talking and mumbling, no change in mental status - still answers the same questions appropriately. Surprised at the low glucose reading and her remaining unchanged. We are at the ER in about a minute and nurses recheck they now have a reading of 12. They try sticking her a good 5 times without success , so doctor comes in and attempts an EJ and misses it - guess he doesn't do them very often - anyhow, doctor resorts to placing a femoral line and it was successful and quite interesting to watch. Dr gives D50, Blood glucose unchanged, pushes another, unchanged.

Well, patient was discharged today and we happened to be the crew that was taking her back - read the chart to see history and according to the chart, the patient was probably never hypoglycemic. I know diabetics have poor circulation, but in this case, the circulation was poor and gave a false reading - they did a stick to her earlobe and found out it was 398. Since they already gave her the D50, and the reading was showing 398 on earlobe and 12 on fingertips. Just thought it was an interesting follow up and wanted to share.

:wacko:
 
Huh. That is very interesting.

I am going to do some reading on this.

It still doesn't seem like it should matter. The blood in the earlobe is still the same blood in the fingers.

Very interesting indeed.
 
Sorry - should have clarified: after D50 was given, subsequent glucose readings were checked by lab work, finger sticks and an earlobe stick. After the D50 administration the finger stick still showed 12, the earlobe stick revealed 398 and the lab work revealed 400 something.:huh:
 
Sorry - should have clarified: after D50 was given, subsequent glucose readings were checked by lab work, finger sticks and an earlobe stick. After the D50 administration the finger stick still showed 12, the earlobe stick revealed 398 and the lab work revealed 400 something.:huh:

AHHH Ok. So in the finger the dextrose wasn't being circulated as well.

Sorry. I am tired.

But still. Thanks for posting. It is easy to get tunnel vision on these "typical calls".
 
So, what did she have? Was her discharge diagnosis sepsis, CHF, or some other critical illness?

Besides just having closure on your story (always good to have!), it might point out why you had the "false-low" reading. It's been demonstrated that capillary glucose levels are unreliable in hypotensive patients, as well as in sick ICU patients. Not so good in patients getting CPR either, but I think you would have mentioned that!

(References pulled out of my review "Using Dextrose in Cardiac Arrest". Good reading if ya got insomnia...)
 
What did the fingers feel and look like before sticking her?
 
Sometimes you really gotta milk those fingers. With all of the things that come with poor distal circulation, and calloused fingers due to repeated sticks, you might get mostly interstitial fluid if you aren't careful.
 
Did she have reynaud's disease? I had a patient like this once who had reynaud's and it's basically poor circulation to the extremities. She had a fsbs of 42 despite several amps of D50. Really strange.
 
Milking the fingers: try grasping the finger firmly near the proximal end (base) then stick. Acts like a tourniquet, versus a milking machine.

Squeezing it like a toothpaste tube can yield a lot of serum, which will confound the test. Had a fellow who LOOKED hypo, milked the fingers by squeezing near the distal ends, and the glucometer read "120". Sent out, ER glucose test was 20 and he was starting seizureform activities.

SO what was her major malfunction?
 
When venous access is obtained (obviously not in your case) I am a believer in using venous blood from the catheter instead of a cap stick. In sick people it's far more current and reliable, and is only a consistent few points off due to the calibration issue.
 
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