No. For example in South Dakota we do not have any special licensing requirement to drive an ambulance. It all depends on what the agency insurance company will cover. One service I worked at you had to be 23. Some services you just need to be 18. Just avoid DUI's. I hear those are no bueno.
not really, however it typically required all employees to be at least 21, which can be advantageous in the eyes of some employers and insurance companies.