As for Silver's study he provided as an exemplar, it still begs the question; While the "markers of oxidative stress" were increased in patients placed on supplemental oxygen, was there any real harm done to those test subjects? Sure, if our entire atmosphere were oxygen-enriched we would undoubtedly see ill effects, but were there any identifiable physical detriments to these patients? As a corollary, how quickly did these markers then fall back to a normal baseline following the termination of the supplemental oxygen? What I mean to ask is, as before, can you find me any case where the administration of O2 - for the length of time that we are with a patient - has done any real harm to a patient? Argue with me all you like about free radicals and antioxidants, but bear in mind that theoretical medicine still does not trump the establishment. I do not care for arguments that provide a "maybe" or a "possibly", but rather for ones that can provide concrete data that can be reproduced.
"Induced hyperoxia is potentially toxic, since it may increase oxidative stress and peroxidative damage to deoxyribonucleic acid, lipids and proteins."
Shall I highlight the words 'potentially' and 'may'? Find me proof! And hopefully not in the form of a 'maybe'!
As for the argument proffered by Tigger, I reassert that the argument about glucose administration being comparative to that of oxygen is in fact a Straw Man argument. Not only is the means of administration different, but glucose has a greater and longer lasting metabolic effect than does oxygen. Giving oxygen to a patient who has a PaO2 of 100 mmHg is not equivalent to giving a patient with a BGL greater than 120 mg/dl glucose or dextrose. There are differences both with administration and effect, so there is no good comparison. If I were to accept this comparison, then should I also accept the following?
A: Sunny days are good.
B: If all days were sunny, we'd never have rain, and without rain, we'd have famine and death.