If you connect your amplifier to your CB, you need to not do that. The FCC does not look very kindly on amplifiers being connected to those radios. Those radios are limited to 4 W output. That is why you need a good antenna system. The more efficient your system is the better output you get. Because of what they do, they make your signal out stronger, but doesn't improve your system's efficiency.
Because increasing CB power output is illegal (by Fed Law), just having an amp in the same vehicle as a CB will be seen by the FCC Enforcement folks as the same as it being hooked up. You can be subject to having your equipment confiscated and up to a $10,000 fine. If you have a HAM license, as long as the amp is NOT connected to the CB's antenna system, no violation occurs. So there's some good to come from having a General class Ham license.