well we certainly know that glucose damages the intima, so i'd posit a theory that it would also cause local irritations in other locations.
What I haven't seen that many people discussing...
Is everyone just tacitly agreeing that this is not the end all be all and shouldn't ever be a 1st line technique (**excluding certain critical presentations**)??
this is a copy of my statement in the IM morphine thread prior to this thread being started in response to the original question of using an IO as an alternative route of administration of analgesia.
"I think it depends on what your treatment goal is...
Are you willing to penetrate not only the skin and deep facial planes, but also bone in a non sterile environment which carries a real infection risk to deliver small doses of analgesia?
Don't forget that while in the emergent setting an IO is not a sterile procedure, in an ICU it is and for a valid reason. In some patients, just like prehospital or ED IV starts, nonsterile IOs are removed and sterile ones inserted.
Using morphine IM allows you to potentiate the effects of the drug by slowing the rate of absorbtion. I don't see why it would be a first line choice for any other reason.
I would look at you wierd if you stuck an IO in a patient to give relatively small doses of analgesics. I would think you seriously underestimate the risks of deep penetration of foreign bodies. I would also be somewhat concerned about your judgement as to what you think was a reasonable use of invasive procedures that were designed to be used in the most seriously ill patients in less critical populations."