reversal agents

[Aidey]

Now that you've posted you could probably get away with a quick google since you cant edit your post.

Most of the reading I've done concerning neurotransmitters focues on their function/effects, not the chemistry, if that makes sense. In the context of how they affect psychiatry and psychology...mind/brain connection stuff (random, I know).

Doesn't haldol affect histamine receptors?

 

[medicRob]

Now that you've posted you could probably get away with a quick google since you cant edit your post.

Most of the reading I've done concerning neurotransmitters focues on their function/effects, not the chemistry, if that makes sense. In the context of how they affect psychiatry and psychology...mind/brain connection stuff (random, I know).

Doesn't haldol affect histamine receptors?

Haloperidol's effects come from its ability to block dopamine receptors (Specifically D2), as well as alpha and serotonin receptors. As far as I am aware, while haloperidol does have blocking effects on cholinergic and histamine receptors, it is actually minimal. However, the blockage of histamine receptors is enough to cause sedation.

 

[Veneficus]

Good work to Jt,

Neuroleptics such as haldol or promethazine inhibit dopamine at the alpha 1 receptor

 

[Veneficus]

for a bonus, and again w/o google,

Why doesn't dopamine have effects on the dopaminergic receptors in the CNS?

 

[TransportJockey]

Good work to Jt,

Neuroleptics such as haldol or promethazine inhibit dopamine at the alpha 1 receptor

Sweet I'll have to thank that medic and also read way more on the subject

 

[8jimi8]

Good work to Jt,

Neuroleptics such as haldol or promethazine inhibit dopamine at the alpha 1 receptor

What is the indicated dose for reversal and what is the max?

 

[zmedic]

Why doesn't dopamine have effects on the dopaminergic receptors in the CNS?

Because it doesn't cross the blood brain barrier. That's why to treat parkinsons you have to give a precursor like L-Dopa

 

[Veneficus]

Because it doesn't cross the blood brain barrier. That's why to treat parkinsons you have to give a precursor like L-Dopa

You are far too esteemed for such a basic explanation