I am always curious about the baseline mental functioning in the elderly patients. There is a new study published in Alzheimer's & Dementia, November 26, 2012 which suggests that after 60 days on an anticholinergic (e.g. benadryl pm, diphenhydramine taken for sleeping problems or some urinary-incontinence rx's ) , 30% of elderly pts suffer a measurable decline in cognitive function. I'll be sure to include those drug questions in my SAMPLE histories...