Estrogen in EMS

[46Young]

I saw this article on firehouse.com today. Has anyone heard anything about this?

http://www.firehouse.com/news/top-headlines/sex-hormones-examined-future-ems-tool-1

Sex Hormones Examined as Future EMS Tool

The female hormone estrogen might be in paramedics' protocols in coming years, some experts say.

By Ed Ballam
-
Firehouse.com News

Posted: Thu, 09/30/2010 - 11:38am
Updated: Thu, 09/30/2010 - 11:42am
..DALLAS, TEXAS -- EMS Expo and Firehouse Central opened Wednesday with some surprising information about the effects of estrogen on cardiac arrest patients and victims of traumatic head injuries.

 

[Veneficus]

Haven't heard of anyone using it yet, but the concept debuted last year. The research is several years old.

The reason it is being pushed for EMS is because it has been demonstrated that the earlier the administration, especially for neuro injuries the better the outcomes.

Similar to the idea for steroids, but steroids turned out not to work.

Did you want to know the mechanisms?

 

[46Young]

Did you want to know the mechanisms?

Absolutely! I'm interested in learning more about this.

 

[abckidsmom]

I clicked on this, expecting to find an article I needed to share with my husband, who tends to snark on women in the fire service and in EMS. Sadly, no go. Now I'm happily sitting back to learn about the mechanism. Thanks, Vene.

 

[Veneficus]

The physio dept. here has ongoing research on it, I will try to track it down tomorrow, in the meanwhile, since it is a rather large topic, here are some good links.

http://www.medscape.com/viewarticle/406718_2

http://stroke.ahajournals.org/cgi/search?journalcode=strokeaha&fulltext=estrogen

http://www.plosone.org/article/info:doi/10.1371/journal.pone.0009421

http://www.jems.com/article/administration-and-leadership/change-agent

 

[Aidey]

I have heard of the concept that estrogen may have some beneficial effects in some cases, I did not know they were talking about bringing it to EMS. One of my friends is a neuroscience major, so I hear about strange brain things.

 

[citymedic403]

Dr Ornato in Richmond VA talked about it a few years ago. His interest in it had to do with the fact that female cardiac arrests go down after puberty and then back up after menopause and they think that estrogen has something to do with it. Unfortunately I only talked to him about it for a few minutes two years ago when I asked him if anything new was coming to ACLS and that’s all I can remember.

 

[Veneficus]

Dr Ornato in Richmond VA talked about it a few years ago. His interest in it had to do with the fact that female cardiac arrests go down after puberty and then back up after menopause and they think that estrogen has something to do with it. Unfortunately I only talked to him about it for a few minutes two years ago when I asked him if anything new was coming to ACLS and that’s all I can remember.

various female sex hormones, particularly estrodiol, inhibit thromboxane A2 and increase NO production.

This thread is about a newer use of the therapy.

 

[medicRob]

Here is a JEMS article that covers it, there are tons of useful references at the bottom.

http://www.jems.com/article/administration-and-leadership/sex-drugs-and-r-r-resuscitatio

 

[Markhk]

The Progesterone in Traumatic Brain Injury (ProTECT) study is now well underway with 11 sites across the nation enrolling patients. It is a phase III, randomized, double-blind placebo controlled study.

http://clinicaltrials.gov/ct2/show/NCT00822900?term=progesterone+in+traumatic&rank=1