Droperidol

JeffDHMC

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Out of curiosity, is anyone out there using droperidol for chemical restraint?

Jeff
 
We use it for its antiemetic properties, primarily for hyperemesis gravidarum and also with Fentanyl to induce neuroleptanalgesia. Its a great drug and the best for pregnant women in regards to cost, efficiency, and maternal / fetal safety. Plus its side effects are mild and easily controlled with Diphenhydramine.

We do not use it for chemical restraint as we have Geodon, Ativan, and elective RSI if needed.
 
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We use haloperidol with an option of chasing it with diazepam.
 
We do not use it for chemical restraint as we have Geodon, Ativan, and elective RSI if needed.

Curious - what dose are you using for ativan?
 
Out of curiosity, is anyone out there using droperidol for chemical restraint?

Jeff

1) OMG we're still using that?! I thought the trials where something goofy like 12% of pts had episodes of Torsades de Pointes kinda said "BAD MOTHER EFFING IDEA" [So, no, I dont use it, ever. Neither the the companies, the hospitals, the pharmacies, nor the assasins carry it near me.]
2) Let us be careful with the term "chemical restraint." The folks in blue don't like that. They think it's mean. (http://www.ncbi.nlm.nih.gov/pubmed/15985915). Seriously though, the FDA says "chemically restraining" a pt is illegal. So, just like we don't bolus propofol (we just "prime the line")...we don't chemically restrain (we just "protect the patient from interfering with their medical care.")
 
But isn't it Denver that is known for using a Versed "dart" (slang for injection) to assist police in making an arrest?

I haven't heard of droperidol being used even in the hospital for several years and had forgotten about it. Wasn't there some big FDA announcement about it a few years ago?
 
Droperidol is not in Denver protocols. As far as sedatives, we have Valium, Haldol, and yes Versed.
 
The "black box" warning from the FDA in 2001 cited a total of 9 reported cases of polymorphic VT over 30 years. All of which occured with doses in excess of 5mg.

http://www.ncbi.nlm.nih.gov/pubmed/12658255

http://www.encyclopedia.com/doc/1G1-175063155.html

Sorry, not clinically significant.........

Droperidol was primarily intended to be and is still heavily used as an antiemetic. Again, it is preferred by many in the OB world as it has been shown to provide better maternal and fetal safety with high efficiency in preventing post op vomiting at the most economical cost.

Personally, I love the stuff (as do my OB pts.!)
 
Nah, no versed dart in Denver that I am aware of. We use it in the hyperadrenergic pt. and that's about it. Thanks for saying what I was going for LP, the box warning for droperidol was a touch extreme. A lot of the issues were seen outside of the U.S. and in doses that would never be considered here, I'm talking 80mg and then some. Haldol has a similar warning.

We're are using it again in Denver. I know not many are using it, starting to look like no one else is though.
 
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