We have Tom Tom GPS'S on our rigs and they are super helpful but you still need to know where you are going because they have gotten me totally lost a few times as well.
I find that the mounted suction container in the rear of our Frazier ambulance doubles nicely as a cup holder. (discliamer: make sure to disinfect and clean thoughly first.)
You stay up for 16 hours
He's been up for 48 straight
You take a warm shower to help you wake up.
The rain in the middle of the interstate keeps him awake.
You complain of a "headache", and call in sick.
He's chilled to the bone, hasn't eaten all day, has the flu, and then runs into a...