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The Quest for the Holy Grail of Trauma Continues
The Science
This multi-center study was conducted to evaluate PolyHeme, which is a hemoglobin-based O2 carrier (HBOC) derived from human blood. It has been demonstrated to have life-sustaining capability. It also has a longer shelf-life than human blood, which makes storage easier than whole blood or packed red-blood cells.
This was a randomized trial of PolyHeme versus traditional crystalloid (NS) in the prehospital setting. Once the patient arrived in the emergency department (ED), the PolyHeme group received up to six units of PolyHeme during the first 12 post-injury hours before receiving blood. Control patients received blood on arrival at the trauma center.
The patients were then followed for their mortality rate at day 30 as well as for their complications (adverse events).
<Snip> Rest HERE:
http://www.jems.com/news_and_articl...edium=email&utm_term=The+Holy+Grail+of+Trauma
- Keith Wesley, MD, FACEP
- Street Science
- 2009 Mar 31
The Science
This multi-center study was conducted to evaluate PolyHeme, which is a hemoglobin-based O2 carrier (HBOC) derived from human blood. It has been demonstrated to have life-sustaining capability. It also has a longer shelf-life than human blood, which makes storage easier than whole blood or packed red-blood cells.
This was a randomized trial of PolyHeme versus traditional crystalloid (NS) in the prehospital setting. Once the patient arrived in the emergency department (ED), the PolyHeme group received up to six units of PolyHeme during the first 12 post-injury hours before receiving blood. Control patients received blood on arrival at the trauma center.
The patients were then followed for their mortality rate at day 30 as well as for their complications (adverse events).
<Snip> Rest HERE:
http://www.jems.com/news_and_articl...edium=email&utm_term=The+Holy+Grail+of+Trauma
