Education about Naproxen (Alleve) cardiovascular safety

mycrofft

Still crazy but elsewhere
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Here is some of the latest info on that:

http://www.medscape.com/viewarticle/820470

Patients ask us about stuff, and this is one study they can be directed to. Have them google "FDA panel Alleve" or some such and talk to their doctor.

The point it is hard to get is that, while aspirin (ASA) is the NSAID which apparently has some helpful properties to prevent or mitigate a heart attack, other NSAIDS can "slip in ahead" before ASA and fill the receptors ASA does its work at…then go away sooner than ASA, leaving the patient at risk. In addition, some (not apparently naproxen, or "Alleve", Naprosyn, etc) can have a deleterious effect (google Vioxx). Alleve/naproxen apparently just isn't that convincing to scientists that it is either safe or helpful in cardiovascular disease. (Includes atrial fib).

Lastly, if their MD has them taking some sort of "blood thinner" besides ASA, they might be able to use another NSAID, but above all they need to ask their MD.

PHEMS concerns: persons on NSAIDS and other anticoagulants including some herbal components like St John's Wort, or alcohol, should be asked about unusual and persistent bruising or bleeding, rectal bleeding, gastric upset, vomiting or belching blood tinged material, or abdominal tenderness over the GI tract.
 
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