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  1. G

    Dextrose 50% Tissue Necrosis??

    Very true nymedic828. I have researched how saline can cause necrosis. I'm just stumped on how actual d50 causes it. I'm not sure if it has to do with it being a hexose sugar. Not sure how toxic hexose sugars are on a cellular level.
  2. G

    Dextrose 50% Tissue Necrosis??

    That is essentially correct but what I'm looking for is deeper. Why is d50 toxic only if it extravasates? It does not harm your skin or damage the vasculature, so why should it only be toxic in the interstitial space? I can't find this anywhere. Also, yes I fully understand solution solubility.
  3. G

    Dextrose 50% Tissue Necrosis??

    We all know that d50 causes tissue necrosis if it extravasated. Why?? What is the PROCESS at work??
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