Errrr, I've done this often. Midaz for seizures and psychotic breaks, naloxone to opiate overdoses, fentanyl, etomidate and rocc or suxs for unconscious RSIs, ACLS drugs to every cardiac arrest I've ever run, calcium for hyperkalemia...the list is long. Not really a good "never".
Of course there are patients that are unable to answer you but in general if they can answer it's a really fantastic idea to ask.