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No, but prostacyclins are.

From what I understand, the effects of NSAIDs would cover for the degradation of the prostacyclin pathway until transcription resumes, which is pretty rapid. So use of ASA would have to be pretty extensive to counteract prostacyclin. All in all, there shouldn't be a scenario in which vitals are...

I had the same concerns with that paper (Pubmed, E. Rey, et al?) I couldn't imagine a response to ASA to such a degree that nitro would be off the table. I appreciate the responses, both.

I apologize, there should be an "n't" at the end of that "would". The last sentence is the most concise question: any experience with a drop in bp associated with ASA which would contraindicate nitro? Any examples of negative interactions at all?

Can anyone think of an instance in which nitro and aspirin would be given together? Maybe lack of a response to one or the other. It seems that even though aspirin is a platelet inhibitor, the potential drop in bp wouldn't be significant enough to worsen the effects of nitro. Research has shown...